In the latest air strikes by Israel
Medics said 20 people died and others wounded on Wednesday in al-Mawasi near Khan Younis.
The Palestinian Civil Defence said the attack set several tents housing displaced families ablaze.
Al Jazeera’s Hani Mahmoud, reporting from Deir el-Balah in central Gaza, said the death toll was expected to rise.
“Patients in the hospital are likely to die because there is no medical care, medical supplies and insufficient medical staff,” Mahmoud said.
“This is not the first time we’ve seen this happening.
There’s a growing frustration among the displaced population in the al-Mawasi evacuation zone,” he said.
Ten people died in an Israeli air strike that hit three houses in Gaza City, the Civil Defence said.
Many victims are still under the rubble with rescue operations underway.
Medics said 11 people died in three air strikes on areas in central Gaza. The dead include six children and a medic. Five of the dead had been queueing outside a bakery, they said.
A further nine Palestinians were killed by tank fire in Rafah near the border with Egypt, medics said.
Israeli forces also fired on Kamal Adwan Hospital in Beit Lahiya in northern Gaza for the fifth straight day, hospital Director Hussam Abu Safiya said.
Three of his medical staff sustained injuries, one critically, on Tuesday night, he said.
“Drones are dropping bombs filled with shrapnel that injure anyone that dares to move,” Abu Safiya said.
“This situation is extremely urgent.”
He said more than 100 patients inside the besieged hospital are at risk of death and Israeli forces are preventing access to the nearby al-Awda Hospital.
Residents in the north’s main three towns – Jabalia, Beit Lahiya and Beit Hanoon – said Israeli forces have blown up dozens of houses.